![]() 3 For example, cancers can be missed at mammography in women with dense breasts because of the camouflaging effect. 2 However, screening with mammography alone may be insufficient for women at high risk of breast cancer. Screening with mammography is associated with a 20% – 40% reduction in breast cancer deaths. Over the course of many decades, medical imaging modalities have been developed and used in routine clinical practice for these purposes in several capacities, including detection through screening programs, staging when a cancer is found, and planning and monitoring treatment. 1 Owing to its high prevalence, the advancement of clinical practice and basic research to predict the risk, detect and diagnose the disease, and predict response to therapy has a high potential impact. ![]() Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer death among women in the United States, with over 281,000 estimated new cases and 43,000 estimated deaths in 2021.
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